The course of Isothermal Titration Calorimetry data analysis

Isothermal Titration Calorimetry (ITC) is widely considered the gold standard technique for the direct determination of binding thermodynamics.
Nowadays, getting kinetic information directly from the thermogram is also possible thanks to the method KinITC implemented in AFFINImeter. Besides KinITC, AFFINImeter offers a number of advanced analytical tools to take the most out of ITC data.

Aiming to show researchers how to make use of these tools, we have prepared a course on ITC data analysis, consisting of a series of video tutorials imparted by Eva Muñoz (Senior Scientist at AFFINImeter) and that we will release in three parts.

The following picture shows the scheme of the course:

The first part, we present three video tutorials dedicated to the analysis of ITC data with KinITC and the multi-temperature tools. Here we are attaching the video tutorials.

  1. Introduction-KinITC automatic processing
  2. KinITC Manual process
  3. Multi-temperature analysis

In the following parts of this course, we will be focused on the design of two binding models for ITC curve fitting with AFFINImeter:

AFFINImeter

AFFINImeter, a new tool to analyze Isothermal Titration Calorimetry data.