This weekend we are joining the leading scientists at the Development in Protein Interaction Analysis (DiPIA) conference. A representative of AFFINImeter will present a new tool to analyze Isothermal Titration Calorimetry Experiments.
New generations of Isothermal Titration Calorimetry (ITC) equipments have significantly improved their performance in terms of higher sensitivity and lower sample size requirements. Thus, physicochemical processes that were undetectable in the past by ITC are now sensed with high precision. In contrast to the progress achieved in instrumentation, ITC data analysis is still limited in many aspects. Researchers often face complicated situations that cannot be represented by standard binding models i.e. the formation of higher order complexes, the presence of multiple candidates to bind the host molecule and/or the simultaneous occurrence of binding and aggregation processes.
AFFINImeter allows to design personalized binding models directly in chemical language, through an original user-friendly interface that allows the design of advanced models.